Yeah the top humans no longer have a chance against computers. It'd be a major success for them just to draw.
Nakamura had an interesting match against a computer a year ago or more. I think they played 4 games, two were at a pawn disadvantage for the program, one the program was an exchange down, and one Naka started with a crazy lead in development, I think Naka went 1-2-1 or something.
I just checked and it was actually 3 draws and 1 loss. The loss, not surprisingly, was game 4 where the only edge was major development. Against a computer the top humans need material advantage over development.