To follow on as to a couple of other matches, (since I've given my opinion on Berrettini and Cressy, as if anyone cares,) I will mention that Jon Wertheim, on the Tennis Channel recap/pre-cap this evening, points out that Rafa should roll Mannarino, and Zverev/Shapo could go long, which could help Rafa. Zverev has been cruising so far, but he hits a higher level of competition this round. DS has beaten him 2/3 of their most recent matches. He's got the pressure of being one of the favorites, AND the pressure of not wanting to have to leave it all on the court v. Shapo, should he face Nadal next. I think he's going to feel the pressure today, and I also think Shapo will pressure him, if not beat him. I'm not seeing the upset, but, TBH, I'd take a long, hard match.
FAA is suddenly playing well, but so is Cilic. I'm inclined to favor Cilic, and I don't especially like him. FAA has a breakthrough hump to get through, and Cilic, playing his best, has won a Major.
Tsitsipas has shown, I think, that the shoulder is not an issue. I like Fritz and his game, so we'll see how this goes, but I think Stephanos goes through.
De Minaur will have the crowd, but Sinner has the game.
Kemanovic runs out of luck v. Monfils.
My predictions, aided by those of others.