Greg Lemond winning the Tour De France in 1989 by 7 seconds... Lemond was an incredible athlete with the second highest ever VO2 max reading of an athlete in any sport ever... He came 2nd in the 1985 tour after being ordered not to ride away from his teammate - French legend Bernard Hinault... won the tour in 1986 (after Hinault attacked him despite saying he would support Lemond in the 86 tour after Lemond had supported the frenchman in the 85 tour).
Lemond was shot by his brother-in-law in a hunting accident during 1986... nobody gave him much of a chance when he returned to cycling of winning the 1989 tour, largely because he was on a poor team and had no decent support riders.
He beat 2 time tour winner on the last stage... usually this is a procession into Paris... but in 1989 it was a time trial. Everything was up for grabs with Laurent Fignon (a 2 time winner) entering the stage with a 58 second advantage.
Lemond won the stage and the tour, riding the fastest time trial in TDF history.
Lemond would win the tour again in 1990... but then EPO (blood Performance Enhancing Drugs) became endemic in cycling... he finished 7th in 1991 before his career petered out due to passive doping (the effects of other riders doping)