I feel like this will be the big test for Roger. I know he beat Del Potro late last year, but facing Tsonga at a Slam will give us a sense of what level Roger is playing at. He hasn't been challenged yet and as far as I can tell hasn't played any players in top 40 even.
I'm not saying he's "done" if he loses to Tsonga, but not only will it be his third Slam in a row going out before the QF (!), but it will tell us that he's not back to being anywhere close to Big Four status - and chances of him ever getting there would be diminishing rapidly.
Also, if he can beat Tsonga then he has a chance against Murray. If he manages to beat both, after that...well, we know that story already.